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| Article Name : | | | IN SILICO CHARACTERIZATION OF STRUCTURAL AND FUNCTIONAL ELEMENTS OF PLA2 | | Author Name : | | | SUMITRAL.BHALERAO , ROHINI R MANE AND V P SINOORKAR | | Publisher : | | | Ashok Yakkaldevi | | Article Series No. : | | | GRT-2451 | | Article URL : | |  | Author Profile View PDF In browser | | Abstract : | | | Natural inhibitors occupy an important place in the potential to neutralize the toxic effects caused by snake venom proteins and enzymes. Snake venom is highly modified saliva containing zootoxins . “Snake venom are highly complex chemical mixture that contains many proteins, mainly particular enzymes, and strongly basic polypeptides”. Neurotoxic venomis fast acting and is rapidly absorbed, attacking the central nervous system. Peptide toxins are usually found inanimal venom associated with specialized envenomationapparatus that allows their delivery into the soft tissue of animals via subcutaneous, intramuscular or intravenous routes. Most venom comprises a highly complex mixture of peptides, often with diverse and selective pharmacologies. Phospholipase A2 causes hemolysis by lysing the phospholipid cell membranes of red blood cells.Amino acid oxidases and proteases are used for digestion. The Therapeutic uses of cobra venom Neurotoxins in ancient China, cobra venom saw its primary use in the treatment of cancer and arthritis. Reportedly the venom was used to treat liver cancer, lung cancer, esophageal cancer, skin cancer, and leukemia. In the Indian Unani system of medicine, cobra venom has been used as a tonic, hepatic stimulant. In India and China, such venoms are administered at specialized medical centers and for an extensive array of applications.SWISS-MODEL is a structural bioinformatics webserverdedicated to homology modeling of protein 3D structures. Homology modeling is currently the most accurate method to generate reliable three-dimensional protein structure models and is routinely used in many practical applications. | | Keywords : | | - Therapeutic uses,
| Article Name : | | | IN SILICO CHARACTERIZATION OF STRUCTURAL AND FUNCTIONAL ELEMENTS OF PLA2 | | Author Name : | | | SUMITRAL.BHALERAO , ROHINI R MANE AND V P SINOORKAR | | Publisher : | | | Ashok Yakkaldevi | | Article Series No. : | | | GRT-2451 | | Article URL : | | | Author Profile View PDF In browser | | Abstract : | | | Natural inhibitors occupy an important place in the potential to neutralize the toxic effects caused by snake venom proteins and enzymes. Snake venom is highly modified saliva containing zootoxins . “Snake venom are highly complex chemical mixture that contains many proteins, mainly particular enzymes, and strongly basic polypeptides”. Neurotoxic venomis fast acting and is rapidly absorbed, attacking the central nervous system. Peptide toxins are usually found inanimal venom associated with specialized envenomationapparatus that allows their delivery into the soft tissue of animals via subcutaneous, intramuscular or intravenous routes. Most venom comprises a highly complex mixture of peptides, often with diverse and selective pharmacologies. Phospholipase A2 causes hemolysis by lysing the phospholipid cell membranes of red blood cells.Amino acid oxidases and proteases are used for digestion. The Therapeutic uses of cobra venom Neurotoxins in ancient China, cobra venom saw its primary use in the treatment of cancer and arthritis. Reportedly the venom was used to treat liver cancer, lung cancer, esophageal cancer, skin cancer, and leukemia. In the Indian Unani system of medicine, cobra venom has been used as a tonic, hepatic stimulant. In India and China, such venoms are administered at specialized medical centers and for an extensive array of applications.SWISS-MODEL is a structural bioinformatics webserverdedicated to homology modeling of protein 3D structures. Homology modeling is currently the most accurate method to generate reliable three-dimensional protein structure models and is routinely used in many practical applications. | | Keywords : | | |
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